Inter vs Shakhtar Donetsk prediction: odds and margins

By Victor Anozie · 2026-10-18 · updated 2026-10-20 08:23 WAT

Inter v Shakhtar Donetsk

Inter are strong favourites at 1.21 against Shakhtar Donetsk at San Siro/Giuseppe Meazza at 20:00 WAT on 21 October. Shakhtar arrive with wins in every recent game, which shapes this tie.

I list each absence once, as the feed repeats names. For Inter, L. Martinez misses with a thigh injury, which leaves you watching who leads the line. C. Jones and B. Pavard also miss with thigh injuries, while J. Stones misses with injury.

Shakhtar miss Eguinaldo with a shoulder injury, K. Fesyun with illness and A. Ghram with injury. V. Korniyenko, P. Obah, T. Puzankov, M. Shved and D. Tvardovskyi are listed as off the roster. I. Azarovi is a doubt with a knee injury.

Inter form:

W 3-1 vs Bologna (away)
L 3-4 vs Club Brugge KV (home)
W 3-0 vs Parma (home)
W 2-0 vs Lumezzane (home)
D 2-2 vs AS Roma (away)

Shakhtar Donetsk form:

W 2-1 vs Kolos Kovalivka (home)
W 3-1 vs AEK Athens FC (home)
W 3-0 vs Veres Rivne (away)
W 3-0 vs Kryvbas KR (home)
W 3-0 vs LNZ Cherkasy (home)

Previous meetings:

Inter 2-0 Shakhtar Donetsk, 2021-11-24
Shakhtar Donetsk 0-0 Inter, 2021-09-28
Inter 0-0 Shakhtar Donetsk, 2020-12-09
Shakhtar Donetsk 0-0 Inter, 2020-10-27
Inter 5-0 Shakhtar Donetsk, 2020-08-17

What the price costs you. At 1xBet Nigeria about ₦16 from every ₦1,000 staked on the result stays as margin. At Betway Nigeria about ₦86 from the same stake stays as margin.

Outcome	Price at 1xBet Nigeria	Chance the price gives	Price without the cut
Home	1.21	82.6%	1.23
Draw	8.35	12.0%	8.48
Away	14.20	7.0%	14.43

My read goes up the evening before kick-off.

Set a limit and stop when you reach it.

Where they stand

Club	Pos	P	Pts	GD	Form
Inter	15	4	6	+2	WWLL
Shakhtar Donetsk	21	4	4	0	LLWD

UEFA Champions League table as of 4 November. Form is the last results in this competition, up to five, most recent first. Full UEFA Champions League table, fixtures and results.

Our other calls on these clubs

3 of 4 right:

Feyenoord 0–3 Inter · Over 2.5 goals · Right
Shakhtar Donetsk 0–1 Sporting CP · Both teams to score · Wrong
Shakhtar Donetsk 3–1 AEK Athens FC · Both teams to score · Right
Inter 3–4 Club Brugge KV · Over 2.5 goals · Right

Every call, with the misses: the full record.

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More UEFA Champions League predictions.